A spokesman for the Ghana Food and Drugs Authority said all imported condoms are supposed to be inspected prior to being disbursed but for an unknown reason these were not.
Officials said the defective condoms come in a silver and white package with a red AIDS ribbon and the words "BE SAFE" written on them, said FDA head Thomas Amedzro.
"Somehow there was a lapse; the batches of the condoms were not submitted as duly required for the appropriate testing to be conducted," he told the BBC Saturday.
The condoms, about 200 million in total, were imported from Kenya and distributed to health groups as part of an anti-HIV/AIDS program and were made by an unidentified Chinese manufacturer. Officials said they've reclaimed 110 million of the condoms so far.
Anyone using them could be at risk of contracting a sexually transmitted disease or unwanted pregnancy.
Officials estimate 230,000 of Ghana's 25 million are living with HIV.