facebook
twitter
rss
account
search
search
 

Aspirin plus drug reduces stroke risk

Feb. 27, 2013 at 12:06 PM   |   Comments

SAN FRANCISCO, Feb. 27 (UPI) -- Stroke patients or those with a transient ischemic attack who added Plavix to aspirin had less risk of a second stroke, U.S. and Chinese researchers say.

Dr. S. Claiborne Johnston, director of the Stroke Service at the University of California, San Francisco, said a minor ischemic stroke is caused by a clot that blocks blood supply to the brain, but its effects are minimal. TIAs and minor strokes don't typically cause permanent harm, but early treatment is critical to prevent the possibility of a major stroke.

"TIAs and minor strokes are emergencies," Johnston, the study's senior author, said in a statement. "If we start dual treatment early, it looks like we can reduce the risk of another stroke by more than 30 percent."

In comparison, aspirin therapy alone cut stroke risk by about 20 percent, he said.

The American Stroke Association said if a person had one or more TIAs, they're almost 10 times more likely to have a stroke than someone of the same age and sex who hasn't.

The Plavix, or clopidogrel, study included 5,174 patients -- median age 62, 34 percent women -- with minor, clot-caused strokes or TIAs from 114 centers in China.

Within 24 hours, treatment was started with either low-dose aspirin -- 75-300 mg on the first day followed by 75 mg/day -- plus a placebo or the same aspirin regimen plus clopidogrel, an initial 300 mg load followed by 75 mg/day for the first 21 days.

The findings were presented at the American Stroke Association's International Stroke Conference.

© 2013 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Recommended UPI Stories
Featured UPI Collection
trending
2014: The Year in Music [PHOTOS]

2014: The Year in Music [PHOTOS]

Most Popular
1
Police search for California man with drug-resistant TB
2
New research explains insomnia prevalence among elderly
3
New data shows Melbourne is most well-rested city in the world
4
New research details rare cancer that killed Bob Marley
5
Daughters more likely than sons to care for elder parents
Trending News
Video
x
Feedback