Stroke is associated with an increased risk of cognitive decline and impairment, and the deterioration of cognitive functions such as memory or thought processing.
Researchers studied whether treatment with B vitamins would help prevent cognitive decline following a stroke.
More than 8,000 recent survivors of strokes or transient ischemic attacks, also called mini-strokes, were randomly assigned to take either a B vitamin pill consisting of 2 milligrams of folic acid, 25 milligrams of B6 and 500 micrograms of B12, or a placebo daily.
About 2,200 patients took a mini-mental state test of their cognition at the study's start and every six months after for a median of 2.8 years.
The study found no notable difference in the incidences of cognitive decline or impairment among participants taking B vitamins compared with the placebo.
The findings were presented at the American Stroke Association's International Stroke Conference in Honolulu.