facebook
twitter
rss
account
search
search
 

FDA approves cholesterol lowering drug

Dec. 26, 2012 at 6:49 PM   |   Comments

WASHINGTON, Dec. 26 (UPI) -- The U.S. Food and Drug Administration approved Juxtapid to reduce low-density lipoprotein, "bad" cholesterol, in those with rare a disorder, officials say.

Juxtapid, or lomitapide, intended for use in combination with a low-fat diet and other lipid-lowering treatments, also lowers total cholesterol, apolipoprotein B, and non-high-density lipoprotein -- non-HDL -- cholesterol in patients with homozygous familial hypercholesterolemia.

Homozygous familial hypercholesterolemia is a rare inherited condition that makes the body unable to remove LDL cholesterol from the blood, causing abnormally high levels of circulating LDL cholesterol. In the United States, homozygous familial hypercholesterolemia occurs in approximately 1-in-1 million individuals, but they often suffer heart attacks and death before age 30.

Juxtapid works by impairing the creation of the lipid particles that ultimately give rise to LDL.

"Juxtapid, in addition to diet changes and other cholesterol-lowering treatments, is a new option for those suffering with homozygous familial hypercholesterolemia and the serious health consequences resulting from this condition," Dr. Eric Colman of the FDA Center for Drug Evaluation and Research, said in a statement.

© 2012 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Recommended UPI Stories
Featured UPI Collection
trending
Celebrity Couples of 2014 [PHOTOS]

Celebrity Couples of 2014 [PHOTOS]

Most Popular
1
Daughters more likely than sons to care for elder parents
2
India asks Pepsi to cut down on sugar in its soft drinks
3
Child vaccination rates are high, CDC says
4
Yoga guru BKS Iyengar dies at 95
5
NIH to test safety of Ebola vaccine candidate
Trending News
Video
x
Feedback