Breast cancer recurrence upped by obesity

Aug. 27, 2012 at 8:15 PM   |   Comments

NEW YORK, Aug. 27 (UPI) -- Obese women diagnosed with breast cancer and treated with standard chemohormonal therapy had worse outcomes than non-obese counterparts, U.S. researchers say.

Lead investigator Dr. Joseph Sparano of the Albert Einstein College of Medicine at the Montefiore Medical Center in New York and therapeutics co-chair of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Breast Committee and colleagues analyzed data from 6,885 women with stage 1 to stage 3 breast cancer.

The women were free of significant co-morbidities; the rate of obesity defined by body mass indexes of 25 percent to 37 percent.

The study, published online ahead of the print edition of the journal Cancer, found even overweight women who were not obese had a higher risk of breast cancer recurring, despite receiving the best cancer treatment.

"We've had a very tumor-centric view of treating cancer and haven't paid much attention to how characteristics of the patient influence prognosis," Sparano said in a statement. "We found a pretty striking relationship between obesity and recurrence of a common breast cancer subtype, which we think may eventually lead to testing new strategies to prevent recurrence."

© 2012 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Recommended UPI Stories
Featured UPI Collection
Notable deaths of 2014 [PHOTOS]

Notable deaths of 2014 [PHOTOS]

Most Popular
Fewer prescription pill overdoses in medical marijuana states
New data shows Melbourne is most well-rested city in the world
New research details rare cancer that killed Bob Marley
Poll: 26 percent of Americans believe they will get Ebola
Daughters more likely than sons to care for elder parents
Trending News