Dr. Rory Hachamovitch of Cleveland Clinic's Heart and Vascular Institute screened more than 3,300 patients who were referred to their medical center for cardiovascular assessment over a one-year period.
Hachamovitch's research team scored responses to a standardized depression test and administered a quality-of-life questionnaire.
In general, minor and major depression were more frequent in women than in men -- 14 percent versus 8.9 percent -- and in heart failure patients -- 22 percent versus 9.6 percent.
Quality-of-life scores were also lower in women and in heart failure patients.
However, the study found the difference in depression and quality-of-life scores was more than double for men with heart failure, compared to all patients.
Women with heart failure also had higher scores than their non-heart failure counterparts, but the difference was significantly less, Hachamovitch said.
The findings were presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions in Atlanta.