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Single vaccine covers ebola and rabies

PHILADELPHIA, Aug. 29 (UPI) -- A new single vaccine protects against both rabies and the Ebola virus, U.S. researchers say.

Matthias Schnell, director of the Jefferson Vaccine Center and a professor at Thomas Jefferson University, says the bivalent vaccines -- tested successfully in mice -- have several advantages over other Ebola candidates that could help speed up development for use in humans and primates.

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"Many Ebola vaccine candidates have been proven effective, but none are close to licensure," Schnell says in a statement. "One of the challenges is the market: There's rather limited incentive in creating a vaccine for Ebola. But these vaccines could change that."

First discovered in 1976, the Ebola virus three of its five distinct species -- the Zaire, Sudan and Bundibugyo species -- are associated with large Ebola hemorrhagic fever outbreaks in Africa, Schnell says.

"Rabies still poses a health threat for people worldwide, and is especially devastating in developing nations where a post exposure treatment is often not available and Ebola still exists in parts of Central Africa and is also a chief bioterrorism concern worldwide," Schnell says. "You can protect these people from two very lethal diseases in an area where they don't have the best access to medical care."

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The findings are published in the Journal of Virology.

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