facebook
twitter
rss
account
search
search
 

Anti-shingles agent discovered

April 26, 2011 at 1:55 AM   |   Comments

ATHENS, Ga., April 26 (UPI) -- U.S. researchers say they discovered a compound that may be more effective than existing agents in treating the very painful blisters involved with shingles.

People age 60 and older who have had chicken pox as children -- caused by the varicella-zoster virus, which can hide in the nerves -- can get shingles, a blistering rash on one side of the body.

Shingles affects as many as 30 percent of mostly elderly Americans and has no specific treatment.

Medicinal chemist Chung (David) Chu of the University of Georgia, one of the inventors of L-BHDA says, it is a novel and effective anti-shingles agent.

"We need new options for medications with increased potency and specificity that can treat VZV, including strains that may be resistant to existing drugs," Chu says in a statement.

Chu and co-inventor Yung-Chi (Tommy) Cheng of Yale University say although there are generic anti-viral drugs to reduce the duration and pain of shingles, and a variety of pain medications and topical creams to relieve long-term pain, they are only moderately effective.

"L-BHDA has the potential to be more effective than existing agents," Chu says.

The compound has been tested in the laboratory and in mice models, the researchers say.

A vaccine to prevent shingles can cut the likelihood of a shingles attack in half, but only a small percentage of older people receive the shot, the researchers say.

© 2011 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Most Popular
1
Colorado researchers working on Ebola vaccine for military Colorado researchers working on Ebola vaccine for military
2
Researchers isolate target for therapies to treat cocaine addiction Researchers isolate target for therapies to treat cocaine addiction
3
Morning exercise helps calm ADHD symptoms in children Morning exercise helps calm ADHD symptoms in children
4
Yoga guru BKS Iyengar dies at 95 Yoga guru BKS Iyengar dies at 95
5
Michelle Obama made a 'Turn Down for What' Vine inspired by turnips Michelle Obama made a 'Turn Down for What' Vine inspired by turnips
Trending News
Around the Web
x
Feedback