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Heart drug may help prevent blindness

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Published: Feb. 21, 2011 at 11:31 PM

ATHENS, Ga., Feb. 21 (UPI) -- A statin drug -- brand-name Lipitor -- may help prevent blindness in people with diabetes, researchers at the University of Georgia College of Pharmacy say.

Lead author Azza El-Remessy and colleagues say diabetic retinopathy is a leading cause of blindness in adults who have had diabetes for 10 to 15 years, and there are no government-approved oral treatments. Surgical methods are expensive and painful, El-Remessy says.

A study using diabetic rats, scheduled to be published in the March edition of the journal Diabetologia, found statins prevent free radicals in the retina from killing nerves important to maintaining vision.

"The exciting part is that there are now treatment options that are proven to be safe that can be immediately translated to patients," El-Remessy says in a statement.

Uncontrolled diabetes and excessive glucose induces free radicals, which causes the eye to release a protein -- pro-nerve growth factor -- which normally matures into nerve growth factor to protect the retinal nerves, El-Remessy explains.

© 2011 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.

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