facebook
twitter
rss
account
search
search
 

COPD: Inhaled steroids pose risk

Nov. 3, 2010 at 4:59 PM   |   Comments

MONTREAL, Nov. 3 (UPI) -- Canadian researchers question the effectiveness of inhaled steroids in the case of patients with chronic obstructive pulmonary disorder.

Researchers at the Jewish General Hospital's Lady Davis Institute for Medical Research in Montreal say oral corticosteroids have been known to increase the risk of diabetes -- more so with higher doses -- but this is the first time the effect has been observed in the inhaled form.

The study, published in the American Journal of Medicine, found inhaled corticosteroids increased the rate of onset of diabetes from 14 people per 1,000 to 19 per 1,000, or 34 percent, every year of use. In other words, 5 additional people for every 1,000 users in the study.

"These are not insubstantial numbers," lead author Dr. Samy Suissa said in a statement. "Over a large population the absolute numbers of affected people are significant. While the benefits clearly outweigh the risk for asthmatics, their effectiveness is questionable in COPD, where they are also used in higher doses. This is a very different risk/benefit situation."

Suissa and colleagues used the extensive databases of Quebec's provincial health insurance board to study nearly 400,000 patients treated for COPD or asthma.

© 2010 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Recommended UPI Stories
Featured UPI Collection
trending
Celebrity Couples of 2014 [PHOTOS]

Celebrity Couples of 2014 [PHOTOS]

Most Popular
1
Enterovirus 68 now sickening children in Northeast Enterovirus 68 now sickening children in Northeast
2
NFL players have 30 percent chance of developing Alzheimer's or dementia NFL players have 30 percent chance of developing Alzheimer's or dementia
3
Morning exercise helps calm ADHD symptoms in children Morning exercise helps calm ADHD symptoms in children
4
Yoga guru BKS Iyengar dies at 95 Yoga guru BKS Iyengar dies at 95
5
The brain takes special notice of winning The brain takes special notice of winning
Trending News
Video
x
Feedback