First PSA may help predict prostate cancer

July 10, 2010 at 11:46 PM

DURHAM, N.C., July 10 (UPI) -- Men with an initial prostate-specific antigen of 10 or higher were 11 times more likely to die of prostate cancer, U.S. researchers suggest.

Researchers at Duke University Medical Center in Durham, N.C., said their findings support routine, early PSA screening for healthy men.

"There has been some controversy over the value of PSA screening beginning at age 40, but the data from this study strongly suggests that early screening can help us stratify patients' risk and identify those who need to be followed most closely from this younger age group. That, in turn, may help save lives," Dr. Judd Moul, the senior author, said in a statement.

The study, published in the journal Cancer, finds men with an initial PSA of less than 4 had a very low risk of death resulting from prostate cancer. Men with a score of 4 to 9.9 were three times more likely to die of prostate cancer than those with PSAs under 2.5.

Moul and colleagues tracked 4,568 men -- median age of 65 -- from the Duke Prostate Center who had PSA tests during the past 20 years and who were diagnosed with prostate cancer. During the study period, 3.5 percent of the men died of prostate cancer while more than 20 percent died of other causes.

Related UPI Stories
Latest Headlines
Trending Stories
Pepsi to release 'Back to the Future Part II' inspired Pepsi Perfect
Nobel Prize in medicine awarded to parasitic disease scientists
Womb transplants begin in U.K. after Sweden's success
Gay Vatican priest comes out day before Pope Francis begins synod on family issues
Scientists find roadmap that may lead to 'exercise pill'