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'Virtual biopsy' colonoscopy promising

JACKSONVILLE, Fla., March 27 (UPI) -- A "virtual biopsy" colonoscopy might soon be able to determine whether a colon polyp is benign without a biopsy, U.S. researchers said.

Dr. Michael Wallace of the Mayo Clinic, in Florida, said currently, colon polyps are extracted during a colonoscopy and sent to a pathologist for examination, which adds time, expense, and some surgical risk, to the procedure.

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In the March issue of Gastroenterology, the researchers report that the most advanced of these two devices, the probe-based Confocal Laser Endomicroscopy, is much more accurate than virtual chromoendoscopy, also known as narrow-band imaging. The pCLE -- an imaging tool only one-sixteenth of an inch in diameter -- can magnify a polyp by a factor of 1,000.

The study found that pCLE was 91 percent accurate in detecting precancerous polyps and narrow-band imaging was 77 percent accurate, when compared to biopsy findings.

"We are getting closer to where we want to be, which is 100 percent accurate," Wallace said in a statement. "Some day soon we will be able to use these probes to virtually biopsy a polyp, removing only those that could become cancerous."

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