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TB booster appears promising

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Published: March. 19, 2010 at 11:27 PM

WORCESTER, South Africa, March 19 (UPI) -- Researchers in South Africa say a booster may help tuberculosis resistance in already vaccinated adults.

Willem Hanekom, co-director of the South African Tuberculosis Vaccine Initiative, reports animal testing of the booster -- Aeras-402 vaccine, developed by Aeras Global Tuberculosis Foundation and Crucell -- has been encouraging. The vaccine has proved safe in healthy adults previously vaccinated with the current TB vaccine.

"Aeras-402 was able to stimulate the immune system in a manner thought to be important for protection against tuberculosis," Hanekom says in a statement. "The world urgently needs new, better vaccines against tuberculosis."

Hanekom says it is important to test the vaccines in settings where the disease is very common, such as South Africa.

The study was published online ahead of print in the American Journal of Respiratory and Critical Care Medicine.

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