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Stem cells 'seed' transplanted windpipe

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Published: March. 19, 2010 at 7:04 PM

LONDON, March 19 (UPI) -- A boy in Britain is doing well four days after surgeons used the boy's own stem cells and a transplanted windpipe to replace his trachea, doctors say.

Martin Birchall of University College London said using the patient's own stem cells and body as a "bioreactor" could transform transplant surgery in the future, the Financial Times reported Friday.

Paolo Macchiarini and colleagues at Careggi University Hospital in Florence, Italy, used enzymes to strip the windpipe of a woman in Italy who died in an accident of all living cells that might trigger immune rejection in the recipient. Macchiarini transported the windpipe to London.

Birchall removed about two tablespoons of stem cells from the boy's bone marrow and injected them into the trachea and replaced it with the boy's defective windpipe.

Friday, the boy said he was breathing better than he had in years, the Times said.

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