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ANN ARBOR, Mich., March 10 (UPI) -- U.S. researchers say they have found a new site in the body where HIV-infected cells may hide.
Scientists at the University of Michigan at Ann Arbor discovered bone marrow -- thought to be resistant to the virus -- may contain latent forms of the infection not affected by current anti-human immunodeficiency virus drug regimens.
The findings, published in Nature Medicine, suggest the virus may target not fully developed long-lived cells that can mature into cells that could carry latent virus.
"Anti-viral drugs have been effective at keeping the virus at bay. However once the drug therapy is stopped, the virus comes back," senior author Dr. Kathleen L. Collins said in a statement. "Ultimately to cure this disease, we're going to have to develop specific strategies aimed at targeting these latently infected cells."
Collins and colleagues examined bone marrow isolated from people infected with HIV and successfully treated with anti-viral drugs for more than six months.
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