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Ginkgo: Risk of seizures in epileptics

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Published: Jan. 30, 2010 at 1:46 AM

BONN, Germany, Jan. 30 (UPI) -- An herbal remedy may raise the risk of seizures in people with epilepsy, German researchers warn.

Eckhard Leistner and Christel Drewke of Institut fur Pharmazeutische Biologie, Rheinische Friedrich-Wilhelms-Universitat, say the remedy -- pills or teas from the leaves or raw or roasted seeds of Ginkgo biloba used to treat an array of maladies including Alzheimer's disease and blood vessel blockages -- contains potentially toxic ginkgotoxin that may affect a chemical signaling pathway in ways that trigger epileptic seizures.

The researchers reviewed 10 studies and they say there is evidence Ginkgo can interact with anti-seizure medications and reduce their effectiveness.

The researchers urge restrictions be placed on the use of the top-selling remedy.

"It is therefore important that the large number of G. biloba product users and their healthcare providers be made aware of these risks, in order to enable them to make informed decisions about the use of these preparations," the study says.

The review is published in the Journal of Natural Products.

© 2010 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.

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