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Weight-loss pill using leptin in the works

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Published: Jan. 28, 2010 at 3:51 PM

MONTREAL, Jan. 28 (UPI) -- Researchers at the University of Montreal say they are developing a pill composed of leptin -- the protein that tells the brain to stop eating.

Moise Bendayan, a pathology professor at the University of Montreal says

leptin regulates appetite in mammals, and its levels decrease when fasting and rise during meals. It has been proven to be an appetite suppressant when administered intravenously to pathologically obese people.

Dr. Philippe Cammisotto, a postdoctoral student and the study leader, is working on the leptin-based, appetite suppressing pill with Bendayan and Emile Levy, also of the University of Montreal.

"Taken orally, such a pill would provide obese people with the sensation of being full. They would eat less and in turn lose weight," Cammisotto said in a statement.

"We hope to start animal testing in 2010, the molecule is easy to synthesize and the protocol is ready."

© 2010 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.

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