facebook
twitter
rss
account
search
search
 

Personalized medicine advancing

Dec. 31, 2009 at 2:10 PM   |   Comments

WASHINGTON, Dec. 31 (UPI) -- New technologies could make treatment tailored to the patient's genetic make-up -- personalized medicine -- a reality, U.S. researchers say.

Researchers at Georgetown Lombardi Comprehensive Cancer Center in Washington report using a new chip -- called DMET for drug-metabolizing enzymes -- to look for hundreds of mutations in as many as 170 genes.

A test unveiling genetic variations that correlate with drug effectiveness and toxicity is needed so the genetic variations -- specifically genes that encode proteins that impact how a drug is metabolized or taken in by the cells -- can be taken into account.

"This type of turn-key testing, if validated, could eventually replace highly-specialized, time-consuming and labor-intensive testing -- thus allowing more institutes the opportunity to pursue genotyping and pharmocogenetic research," John Deeken says in a statement.

Deeken and colleagues report their results testing the genotyping platform DMET in The Pharmacogenomics Journal.

"DMET appears to offer great promise in this field as a reliable test unveiling genetic variations that correlated with drug effectiveness and toxicity," Deeken says in a statement. "Still, DMET isn't yet ready for prime time in terms of having received Food and Drug Administration approval, but we're getting closer."

© 2009 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Most Popular
1
CDC: Get your flu vaccine CDC: Get your flu vaccine
2
Study shows one dose of antidepressants changes the brain Study shows one dose of antidepressants changes the brain
3
16 U.S. food makers surpass calorie-counting pledge 16 U.S. food makers surpass calorie-counting pledge
4
Morning exercise helps calm ADHD symptoms in children Morning exercise helps calm ADHD symptoms in children
5
Yoga guru BKS Iyengar dies at 95 Yoga guru BKS Iyengar dies at 95
Trending News
Video
x
Feedback