facebook
twitter
search
search

Heart failure linked to vitamin D gene

Dec. 3, 2009 at 11:54 AM

ANN ARBOR, Mich., Dec. 3 (UPI) -- U.S. researchers linked congestive heart failure to a gene variant affecting vitamin D activation.

The study, published in the journal Pharmacogenomics, showed patients with high blood pressure who possess a gene variant that affects an enzyme critical to normal vitamin D activation are twice as likely as those without the variant to have congestive heart failure.

"This study is the first indication of a genetic link between vitamin D action and heart disease," Robert U. Simpson of the University of Michigan Medical School said in a statement.

"This study revealed that a critical enzyme absolutely required for production of the vitamin D hormone has a genetic variant associated with the development of congestive heart failure."

If subsequent studies confirm the finding and demonstrate a mechanism researchers may be able to screen earlier for those most vulnerable and slow the progress of heart failure, Simpson said.

Related UPI Stories
Latest Headlines
Trending Stories
Device shown to 'smell' prostate cancer in men in trial
Scientists confirm second, more intense form of Lyme disease
Study: Sending fewer men to prison may slow spread of HIV
Einstein vindicated: Scientists find gravitational waves
Biden gathers forces to end cancer: Can he make a difference?