facebook
twitter
rss
account
search
search
 

Urate linked to slowed Parkinson's disease

Oct. 15, 2009 at 2:38 PM   |   Comments

BOSTON, Oct. 15 (UPI) -- U.S. researchers have found Parkinson's disease progresses more slowly in patients with higher levels of urate.

Urate is a salt derived from uric acid. When the body cannot metabolize uric acid properly, urates can build up in body tissues or crystallize within the joints.

The study, published online in the Archives of Neurology, found the disease progressed more slowly in patients with the highest levels of urate than in people with the lowest levels.

Study leaders Dr. Michael Schwarzschild of Massachusetts General Hospital and Alberto Ascherio of Massachusetts General Hospital, both in Boston, said it is unknown whether the higher levels of urate actually protect Parkinson's patients or serves only as a marker of protection.

High levels of urate accumulated in the blood are known to cause gout -- a form of arthritis, especially in the big toe -- and other problems.

Schwarzchild and Ascherio based their study on data from a larger study collecting blood samples -- called DATATOP -- begun by Dr. Ira Shoulson of the University of Rochester Medical Center two decades ago. DATATOP collected blood samples, cerbrospinal fluid, and other information over an eight-year period from 800 people with Parkinson's Disease.

© 2009 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Recommended UPI Stories
Featured UPI Collection
trending
Celebrity Couples of 2014 [PHOTOS]

Celebrity Couples of 2014 [PHOTOS]

Most Popular
1
Daughters more likely than sons to care for elder parents
2
India asks Pepsi to cut down on sugar in its soft drinks
3
Child vaccination rates are high, CDC says
4
Yoga guru BKS Iyengar dies at 95
5
NIH to test safety of Ebola vaccine candidate
Trending News
Video
x
Feedback