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Garlic compound a potential diabetes drug

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Published: Nov. 20, 2008 at 11:50 AM

MATSUSAKA, Japan, Nov. 20 (UPI) -- A drug based on a chemical found in garlic has treated type 1 and type 2 diabetes in mice, researchers in Japan said.

Hiromu Sakurai and colleagues from the Suzuka University of Medical Science gave the drug based on vanadium and allaxin -- a compound found in garlic -- orally to type I diabetic mice. The researchers said they found it reduced blood glucose levels.

In previous work, the researchers had discovered the vanadium-allaxin compound treated both diabetes types when injected, but this new study shows the drug has promise as an oral treatment for the metabolic disease, the researchers said.

Type I diabetes is currently treated with daily injections of insulin, while type 2 diabetes is treated with drugs some bearing side effects, Sakurai said.

The findings were published online ahead of print an issue of the Royal Society of Chemistry's journal Metallomics.

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