ADHD drugs don't cause genetic damage

Published: Nov. 20, 2008 at 8:33 PM
Order reprints
BETHESDA, Md., Nov. 20 (UPI) -- Two common medications used to treat attention-deficit hyperactivity disorder do not appear to cause genetic damage in children, U.S. researchers said.

Research at the National Institutes of Health and Duke University Medical Center in Durham, N.C., provides new evidence that therapeutic doses of stimulant medications, such as methylphenidate and amphetamine, do not cause cytogenetic, or chromosomal, damage in humans.

The study, published in the Journal of the American Academy of Child and Adolescent Psychiatry, looked at three measures of cytogenetic damage in white blood cells of each child participating in the study, and found no evidence of any changes after three months of continuous treatment.

"This is good news for parents," said study co-author Kristine L. Witt, a genetic toxicologist at the National Institute of Environmental Health Sciences. "Our results indicate that methylphenidate- and amphetamine-based products do not induce cytogenetic damage in children."

However, the researchers emphasize that the findings should not be interpreted as final proof of the long-term safety of stimulant drugs for the treatment of ADHD.

"More research and close monitoring of children taking these medications for extended periods of time is needed to fully evaluate the physical and behavioral effects of prolonged treatment with stimulants," study co-author Scott H. Kollins of Duke University said.


© 2008 United Press International, Inc. All Rights Reserved.



Anglican bishop: Gays must repent (2 min)
Living statues coming to London square (7 min)
Disney World monorail driver dies in crash (19 min)
Obesity increasing among poor Brit kids (22 min)
Tennesseans remember Steve McNair (23 min)
UPI NewsTrack TopNews (24 min)
Southern China battered by flooding (38 min)
Photoshop this rugged race
Afghanistan as a major tourist destination? The tag says it all
If you've been getting unemployment in Indiana, and haven't put on your really, truly bestest effort...
63 years ago today, the bikini was introduced
Sarah Palin has apparently hired someone with a GED in Law, threatens to sue bloggers for defamation...
If you have a beer belly, blame your dad, not all the beer you've been drinking since you were 14...