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SEATTLE, April 29 (UPI) -- A medication used to prevent fractures in women with osteoporosis, may be linked to a heightened risk of abnormal heart rhythm, a U.S. study said.
The medication, alendronate, may be associated with an increased risk of atrial fibrillation, says a study published in the Archives of Internal Medicine.
Dr. Susan R. Heckbert of the University of Washington and Group Health in Seattle and colleagues studied 719 women with confirmed atrial fibrillation that began between 2001 and 2004 and 966 control women of same age with no atrial fibrillation.
After adjusting for other risk factors, those taking alendronate were linked to a higher risk of atrial fibrillation compared with those who had never taken any bisphosphonate -- a class of drugs that help prevent osteoporosis.
The researchers estimate that about 3 percent of new atrial fibrillation cases in this population may be attributed to alendronate use, the study said.
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