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Breast cancer different before/after 70

BERLIN, April 21 (UPI) -- As women approach age 70, they become less likely to be diagnosed with aggressive tumors that spread to the lymph nodes, a Belgium study said.

Study leader Hans Wildiers of University Hospitals Leuven, Belgium, found women's risk of positive lymph nodes decreased by 13 percent for each decade they aged -- up to age 70. However, after age 70 the odds of lymph node involvement doubled with every 10-year increase in age -- in women who had tumors that were no bigger than 15mm across. If the tumors were larger than 42 to 43 mm the risk of lymph node involvement continued to decrease.

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Wildiers and his team investigated 2,227 breast cancer patients between 2000 and 2006 at the Hospitals Leuven and compared results with a separate database of over 11,000 breast cancer patients on the Eindhoven Cancer Registry.

"The effect of age of lymph node positivity is not straightforward," Wildiers said in a statement. "There is an interaction between age and tumor size, suggesting that, up to the age of 70, age mainly has a positive effect ."

The study results were reported at the 6th European Breast Cancer Conference in Berlin.

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