ANN ARBOR, Mich., June 11 (UPI) -- Iodine-containing contrast agents can produce allergic types of reactions, but they are rare in children, according to a U.S. study.
Allergic-like reactions to newer iodine-containing contrast agents -- nonionic contrast media -- are rare in children, according to a study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Children's Hospital, both in Ann Arbor, Mich.
"We performed our study because we wanted to find out what the exact risk of allergic reactions to these newer contrast agents was in children," said lead author Dr. Jonathan R. Dillman in a statement.
The study evaluated 11,306 pediatric IV administrations of iodine-containing contrast agents over a seven-year period. Acute allergic-like reactions were documented in 20 of the patients and of these patients, 16 of the allergic-like reactions were categorized as mild, one as moderate, and three as severe, according to the study published in the June issue of the American Journal of Roentgenology.
Six of the reacting patients had a history of allergic-like reactions, including two patients who had a history of reactions to iodinated contrast material. Five of the patients had a history of asthma.
