Nautilus OK'd to test hep C drug

Published: May 14, 2007 at 10:44 AM

PARIS, May 14 (UPI) -- Nautilus said Monday the U.S. Food and Drug Administration cleared its potential hepatitis C treatment, oral Belerofon, for a phase 1 trial.

Belerofon is a formulation of interferon-alpha that is intended to last longer in serum and reach blood levels comparable to those obtained by injected products.

"The development of an orally administered Interferon-alpha highlights the potential of Nautilus Biotech's technology platform," said Paul Martin, the firm's vice president of strategy. "It represents the promise of a third generation of therapeutic protein drugs that can be taken more easily and have great commercial potential to replace established injectable products."

The phase 1 trial of Belerofon is scheduled to begin later this year. Nautilus said it will be an open-label, ascending dose study of four doses of the investigational compound.

© 2007 United Press International, Inc. All Rights Reserved.
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