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7 walnuts a day deliver health benefits
CHAPEL HILL, N.C., March 8 (UPI) -- Schizophrenics not responding to the older anti-psychotic drug perphenazine did better on a newer drug, quetiapine, say U.S. scientists.
The research was part of the ongoing Clinical Antipsychotic Trials of Intervention Effectiveness study and was led by Scott Stroup at the University of North Carolina at Chapel Hill.
The team randomly selected 257 schizophrenic patients to take the older anti-psychotic drug perphenazine. Among the 192 patients who discontinued the medication because it was ineffective or produced bad side effects, 114 got one of three newer anti-psychotic drugs: olanzapine, quetiapine or risperidone.
Those taking quetiapine stayed on their new medication an average of 10 months before stopping. The olanzapine group took their meds an average of seven months, and those taking risperidone discontinued it after an average of only four months.
The main adverse side effect in the study was weight gain and metabolic disturbances, but none of those taking quetiapine stopped the drug for these reasons.
The research appears in the March issue of the American Journal of Psychiatry.
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