facebook
twitter
rss
account
search
search
 

HGSI's Albuferon for hepatitis C advancing

March 14, 2006 at 11:09 AM   |   Comments

ROCKVILLE, Md., March 14 (UPI) -- Human Genome Sciences said its hepatitis C treatment Albuferon showed strong anti-viral activity in phase 2 trials.

David Stump, HGSI's executive vice president of drug development, said the company's phase 3 trials could be launched by the end of the year.

In the phase 2 study, 30 percent of the patients in the lower-dose treatment groups did not have detectable levels of the hepatitis C virus at the end of treatment, or week 48. This percentage dropped to 18 percent at the 12-week follow-up. HGSI said they considered the data positive because nearly two-thirds of the study participants had failed on previous treatment regimens.

In a phase 2b trial in interferon alpha-naive patients, Albuferon showed a trend toward being comparable to Pegasys with less frequent dosing. Approximately 75 percent of patients receiving Albuferon every 2 weeks exhibited a level of hepatitis C viral load below the level of quantitation at 12 weeks, compared with 66 percent of patients receiving Pegasys at seven-day intervals.

© 2006 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Most Popular
1
Protein found in breast milk may protect infants from a certain disease
2
Morning exercise helps calm ADHD symptoms in children Morning exercise helps calm ADHD symptoms in children
3
CDC: Get your flu vaccine CDC: Get your flu vaccine
4
Yoga guru BKS Iyengar dies at 95 Yoga guru BKS Iyengar dies at 95
5
New industry-baked marijuana PSAs advise moderation New industry-baked marijuana PSAs advise moderation
Trending News
Video
x
Feedback