BRONX, N.Y., Dec. 26 (UPI) -- A gene variation that helps people live long lives also protects their memories and their ability to think and learn say U.S. researchers.
Nir Barzilai and his colleagues at the Institute for Aging Research at Albert Einstein College of Medicine in the Bronx, N.Y., studied a group of 282 older Ashkenazi Jews whose ancestors came from northern Europe. The cohort contained 158 people 95 and older and 124 people between 75 and 85. Those who had the gene variant were twice as likely to have good brain function as those who did not.
The team discovered that the variant increases the size of cholesterol particles in the blood, making them much less likely to lodge in blood vessel linings and cause heart attacks and strokes. They also thought the altered gene may protect against the development of Alzheimer's disease, although they are not sure how it does so.
Barzilai said that scientists are currently trying to develop drugs to mimic the effect of the gene variation for people who don't possess it.
The research was published in the December 26 issue of the journal Neurology.
