The 55-year-old actor sports a wig, makeup and pearls to emulate Dreyfus as Veep president Selina Meyer, while the 53-year-old actress slicks back her hair and gets her hands bloody to imitate Spacey as president Frank Underwood from House of Cards. The startling exchange covers the magazine's 25 Best Characters on TV issue; Underwood topped the list, with Meyer right behind at No. 2.
House of Cards is a Netflix original drama, while Veep is a comedy created by Armando Iannucci (The Thick of It, In the Loop) for HBO. House of Cards was renewed for a third season in February, while Veep was renewed for a fourth in June.
Entertainment Weekly's 25 Best Characters on TV issue hits newsstands Friday.