The network announced the move in a statement.
"Unfortunately, The Arsenio Hall Show will not return for a second season; while there are many loyal fans of the show, the series did not grow its audience enough to continue," CBS Television Distribution said. "Arsenio is a tremendous talent and we'd like to thank him for all the hard work and energy he put into the show. We'd also like to thank Tribune and all our station group partners for their support of the show."
Hall said he knew the show "would be a challenge."
"I'm gratified for the year we've had and proud of the show we created. I'd like to thank everyone on my staff for rallying around me and striving to make the best show possible every night," he said.
The late-night talk show aired on 17 stations in most markets at the 11 p.m. slot, going head-to-head with local news. The second half hour of the show conflicted with major network late-night talk shows like the Tonight Show with Jimmy Fallon, Jimmy Kimmel Live and the Late Show with David Letterman.
The Arsenio Hall Show debuted with a solid 1.5 rating, but later took a dive, dropping 60 percent in the key demographic within the first several months.