The 39-year-old actor joined the CW series in 2008 as the angel Castiel. He was credited as a recurring character for the fourth season and became a series regular for the fifth and sixth seasons. He was later credited as a special guest star during the seventh and eighth seasons and became a series regular for the current ninth season.
Fans will find out about Castiel's fate when Supernatural's ninth season finale airs Tuesday, May 20th.
Collins has also starred in several motion pictures including Stonehenge Apocalypse, Girl Interrupted, Karla and Over Her Dead Body.
Notable deaths of 2014 [PHOTOS]