The couple, who got in engaged last year, were the first same-sex couple to be married at the New York landmark.
Berkus wore a J. Crew suit and Brent wore Saint Laurent, and they exchanged gold bands from Van Cleef & Arpels.
The festivities were planned by Marcy Blum Associates, invitations were done by Elum Designs and Berkus' own fabric line for Target stores was used in the decorations.
Sheri Salata, president of the OWN network, officiated.