"It is with great sadness that we confirm that John Henson, son of Jim and Jane Henson and brother to Lisa, Cheryl, Brian and Heather, died at age 48 of a sudden massive heart attack on Friday ... while at home with his daughter," The Jim Henson Co. of Los Angeles said in a statement on its Facebook page.
John was a member of the company's board.
A private service was being planned, the statement from the family-run business said.
Jim Henson died in 1990 and Jane Henson passed away last April.
Celebrity Families of 2014 [PHOTOS]