The beloved star headlined the blockbusters "The Heat" and "Gravity" in 2013.
"Gravity" also won the People's Choice Award for Favorite Dramatic Movie, while "The Heat" was named Best Comedic Movie. Bullock and her "Gravity" co-star George Clooney won the honor for Favorite Movie Duo.
Joking about how the many wins made it look like she spent "a lot of lonely Friday nights voting for myself," Bullock added, "I've learned so much this year."
She then thanked all of the creative artists who worked on her movies to make her look so good.
"Despicable Me 2" won the title of Favorite Family Movie.
Robert Downey Jr. earned the Favorite Action Movie Star honor and his blockbuster "Iron Man 3" was named both Favorite Movie and Action Movie.
"The Big Bang Theory" won the Best Network Comedy Series honor, while co-star Kaley Cuoco was voted Favorite Comedic TV Actress.
"Glee" standout Chris Colfer was declared Favorite Comedic TV Actor.
"The Good Wife" won the prize for Favorite Network TV Drama, while cast member Josh Charles was named Favorite Dramatic TV Actor.
"Castle" won the Favorite TV Crime Drama trophy, and its leading lady Stana Katic earned the accolade for Favorite Dramatic TV Actress.
The Favorite Daytime TV Host award went to Ellen DeGeneres, while the Favorite New Talk Show Host title was given to Queen Latifah and the Favorite Late-Night Host trophy went to Stephen Colbert. "The Voice" was named Favorite Competition Series.
Justin Timberlake took home the Favorite Album statuette for "The 20/20 Experience," as well as the awards for Favorite Male Artist and Favorite R&B Artist. Britney Spears won the prize for Favorite Pop Artist.