The "Mighty Aphrodite" and "Romy and Michele's High School Reunion" actress will appear in multiple episodes of Season 4 of the show, the cable network said.
She will play Sara, "a woman far removed from her former life as a graphic designer," TNT said in a news release. "She is now dogged by death at every turn, yet she has never felt more alive, free or fearless."
Starring Noah Wyle, the show is about life and survival in the wake of a catastrophic alien invasion. The cast also includes Moon Bloodgood, Will Patton, Drew Roy, Connor Jessup, Maxim Knight, Seychelle Gabriel, Mpho Koaho, Colin Cunningham and Sarah Carter.