The small-screen project will be based on the upcoming biography "Carson the Magnificent: An Intimate Portrait" by Bill Zehme.
The miniseries will cover Carson's 30-year run -- from 1962-92 -- as host of "The Tonight Show," as well as his childhood growing up in Nebraska, his often secluded off-camera life and friendships he made throughout his career, the network said in a release.
Casting for the TV icon will be named at a later date, NBC said.
Carson died in 2005 from complications of emphysema. He was 79.