"Up Late w/Alec Baldwin" is to air Fridays from 10-11 p.m. ET., starting in October.
The announcement was made by Phil Griffin, president of MSNBC.
"After two seasons of my WNYC podcast, I've developed a fondness for hosting a show that involved talking with smart, talented and engaging people in every imaginable field," said Baldwin in a statement. "I'm grateful to MSNBC for helping me bring a similar show to television."
"I've been talking with Alec for a while and can't wait to bring his personality and eclectic interests to MSNBC," said Griffin. "He's got such passion for ideas and what's going on in the world -- he's going to be a great addition to our line-up."