The group is to sing the song from their new album "In a World Like This" on the show Wednesday night.
All five original members -- Nick Carter, Howie Dorough, Brian Littrell, A.J. McLean and Kevin Richardson -- are celebrating the 20th anniversary of the Backstreet Boys with the release of their latest album Tuesday.
The band is to kick off a North American concert tour Friday.
2014: The Year in Music [PHOTOS]