"He'd like you to please consider being his wife, being his bride," Braff tells Matt Hulbert's, girlfriend Janice.
The video then features a montage of various people and animals in the couple's lives holding signs that read, "Say yes."
"You're never going to score anyone else this hot," Braff told Hulbert at the end of the video before singing Beyonce's engagement anthem "Single Ladies (Put a Ring On It)."
Hulbert then asks for Janice's hand in marriage and she happily accepts, Zap2it.com said.
Janice's last name was not reported.
About 500,000 people viewed the clip on YouTube since it was posted Tuesday.