The pop star will perform and sit down for chats with Fallon each night from March 11-15.
This will be the first time any featured artist has appeared on every "Fallon" show during a single week, NBC said.
Timberlake's album is set for release March 19 on RCA Records.
Notable deaths of 2014 [PHOTOS]
Yvette Nicole Brown departs sitcom 'Community'