Rowe has starred on the show since 2003.
"A few weeks ago, I was officially informed that 'Dirty Jobs' had entered into a new phase," Rowe wrote in a blog post.
"One I like to call, 'permanent hiatus.' Or in the more popular industry vernacular, canceled," he wrote. "'Dirty Jobs' is a very personal show, and it's difficult for me to imagine a future that does not involve exploding toilets, venomous snakes, misadventures in animal husbandry, and feces from every species. ...
"I can't say that 'Dirty Jobs' never jumped the shark [since I literally leaped over one in Season 2,'] but I'm proud to say it's still the same hatchet. The last episode looked pretty much like the first. We didn't become something we weren't. We never shared the sewer with Paris Hilton, and we never invited you to 'tune in next week for a very special '"Dirty Jobs."' We stuck to the mission statement. We stayed small. We worked hard. And we had a hell of a good time. It was, as they say, a very good run."
EW.com said Wednesday declining ratings were to blame for the show's demise.
Rowe will continue in his job as narrator of Discovery Channel's "Deadliest Catch," EW.com said.