Tamblyn, 29, is best known for her work on TV's "General Hospital," "Joan of Arcadia" and "House, M.D.," as well as in the "Sisterhood of the Traveling Pants" movies.
Cross, 48, is known for his roles on "Mr. Show," "Arrested Development," "The Increasingly Poor Decisions of Todd Margaret" and "Modern Family."
The couple announced their engagement in August 2011.
People.com said music at the Saturday wedding was provided by Yo La Tengo and disc jockey Questlove of The Roots.
Swim Week Miami Beach 2014 [PHOTOS]