Gore, former U.S. vice president and Current's co-founder, will appear on Tuesday's debut episode to welcome comedian and television personality Joy Behar to the network.
Gore is expected to talk with Behar on politics and share his thoughts on the Democratic and Republican conventions, the network said.
Other guests confirmed for next week include Susie Essman and Alan Colmes.
"Joy Behar: Say Anything" will air on Current Monday through Thursday at 6 p.m. ET.