Giuliana Rancic, who is a breast cancer survivor, announced Monday on the "Today" show she and her husband will soon be parents because their surrogate is pregnant.
She said she and Bill know the baby's gender but aren't revealing it right now.
The birth to a gestational surrogate means the baby will be the Rancics' genetic child.
"We are so thrilled that our prayers have been answered," she separately told E! News.
"We are absolutely ecstatic to be sharing this with everyone who has been following our journey," her husband said.
People.com said Giuliana has suffered numerous health issues in recent years. She had a miscarriage in 2010, underwent fertility treatments to try to get pregnant again, then had a double mastectomy last year as part of her cancer treatment.
The Rancics star on Style Network's, "Giuliana & Bill," which is in its fifth season.