The show is executive-produced by Vince Vaughn, Peter Billingsley and Rob Long.
Byrne also serves as producer on the series, which comes to TBS from Vaughn's Wild West Picture Show Productions, in association with Warner Horizon Television.
The pilot was co-written by Byrne and Long, with Ted Wass directing. It is slated to premiere this summer.
"'Sullivan and Son' is a smart, funny, workplace comedy from the distinct comedy voices of Steve Byrne and Rob Long," Michael Wright, executive vice president and head of programming for TBS, TNT and Turner Classic Movies, said in a statement.
"The bar-stools at Sullivan's bar are filled with outrageous, unique characters, and Steve and Rob have created an outstanding world in which they can shine. We are extremely proud of this show and look forward to spending many nights throwing one back with the regulars at Sullivan & Son."