"Castle" was named Favorite TV Crime Drama, while its star Nathan Fillion earned the Favorite TV Drama Actor accolade.
"Mother" was voted Favorite Network Comedy and cast member Neil Patrick Harris Favorite TV Comedy Actor. Pop star Katy Perry won the award for Favorite TV Guest Star for her appearance on "Mother."
Perry, who canceled her plans to attend the ceremony after her husband, comedian Russell Brand, filed for divorce, also won the awards for Favorite Female Artist and Favorite Tour Headliner, Favorite Song of the Year for "E.T." featuring Kanye West and Favorite Music Video for "Last Friday Night."
"Glee's" Lea Michele was declared Favorite TV Comedy Actress and Nina Dobrev from "The Vampire Diaries" Favorite TV Drama Actress.
"Supernatural" took the prizes for Favorite Network TV Drama and Favorite Sci-Fi/Fantasy Show, while the Favorite Cable TV Drama title went to "Pretty Little Liars."
Fans chose Jimmy Fallon as Favorite Late Night TV Host and "Hot in Cleveland" as Favorite Cable TV Comedy.
Kaley Cuoco, one of the stars of "The Big Bang Theory," served as host of the 38th annual People's Choice Awards ceremony, which aired on CBS.