Kolb will report directly to Bonnie Hammer, chairman of NBCUniversal Cable Entertainment and Cable Studios.
Kolb previously served as president of marketing, news and online for E! and The Style Network.
"As a member of E!'s leadership team, Suzanne has played a pivotal role in getting the network to the great place it is today," Hammer said in a statement. "Her strong oversight of three areas key to E!'s success -- news, online and marketing -- makes her the perfect person to lead the brand through the important next phase of its evolution."
"I am incredibly grateful to Bonnie for the opportunity to lead E! during this wonderfully exciting and unique time in the brand's history and equally thrilled to do that in partnership with a management team I know and love," added Kolb. "E! has enjoyed great success in the past but we're just getting started."
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