The cable network has also been home to "Tyler Perry's House of Payne" and Perry's "Meet the Browns."
As with those shows, syndication for "Better" will be sold by Debmar-Mercury.
"Better" follows the "ups-and-downs of married life for Marcus and Angela, two characters who originated in the feature films 'Why Did I Get Married' and 'Why Did I Get Married Too?'" TBS said in a synopsis.
Michael Jai White and Tasha Smith are to reprise their movie roles of television news anchor Marcus and salon owner Angela in the small-screen version of the movies.
Additional cast members are expected to be announced soon, TBS said.
Production on the series is to begin this summer at Tyler Perry Studios in Atlanta.
"Tyler Perry's series have been tremendously successful for TBS, helping establish the network as a prime destination for African-American viewers," Michael Wright, executive vice president and head of programming for TBS, TNT and Turner Classic Movies, said in a statement Tuesday. "Given such a remarkable track record, we're excited for the opportunity to expand our relationship with Tyler Perry and Debmar-Mercury with the new series 'For Better or Worse.'"