Her episode is scheduled to air in May.
Wilson will play Bree Mazelon, the protective mother of a teenager under investigation in the installment titled "Delinquent."
"A few years ago, I saw Rita Wilson give a riveting performance playing the mother of child with ADD in the play 'Distracted,' and I knew she'd be a wonderful guest star for 'SVU.' Rita will be playing a mother struggling to care for her seriously disturbed child and we know the episode will be truly memorable," Executive Producer Neal Baer said in a statement.
Wilson recently guest-starred on two episodes of CBS's "The Good Wife." Her film credits include "It's Complicated," "The Bonfire of the Vanities," "Sleepless in Seattle," "Mixed Nuts," "Runaway Bride," "The Story of Us," "My Life in Ruins" and "Old Dogs."
Wisconsin business offering 'therapeutic cuddling' forced to close
Puzzle-maker slips 'Murdoch Is Evil' into Rupert Murdoch's Sunday Telegraph